Welcome to the Boland lab!

We are a friendly, focused and enthusiastic group working at the intersection of Structural Biology, Molecular Biology and Cell Biology. We leverage the latest developments in Structural Biology, and here in particular cryo-electron microscopy (cryo-EM) with complementary biophysical techniques (proteomics, light-microscopy, microfluidics, etc.), to adress complex biological questions in the field of cell cycle regulation and cell signaling.

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LATEST NEWS

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WELCOME TO THE LAB XUEFENG!

We are very happy to have you as part of our lab and look forward to your start in September. Your expertise in GPCR purification will be a great asset to the group. Welcome, and we wish you great success!

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PAPER ON S100A9 OUT IN NATURE COMMUNICATIONS

A collaboration with the Coppari group at the University of Geneva on S100A9 is now out in Nature Communications. Anna Höfler purified recombinant proteins used for in vivo studies. 

https://www.nature.com/articles/s41467-022-31803-5.pdf

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THE APC/C AT SUB-3 Å RESOLUTION

Anna and Jun have deposited the first sub-3 Å structure to the EMDB/PDB of the Anaphase-promoting complex/cyclosome (APC/C) - even before paper publication (see structure gallery). We hope that the more complete and accurate model will already be useful for scientists working on cell cycle regulation.
PDB code: 7QE7, release date: 22.12.22

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PROJECT FUNDED!

A new collaboration between the Stoeber lab at the CMU (Faculty of Medicine) and the Boland lab (Faculty of Sciences). Very much looking forward to this project, Miriam & coworkers!

 

RESEARCH PROJECTS

Our Current Focus

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STRUCTURE AND FUNCTION OF CELL CYCLE REGULATORY PROTEINS

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MEMBRANE PROTEINS INVOLVED IN ENERGY METABOLISM

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UNDERSTANDING THE MOLECULAR BASIS OF METABOLIC PROTEIN CLUSTERS

 

LAB MEMBERS

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ANDREAS BOLAND

Principal Investigator

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YVAN PFISTER

Research assistant

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CAROLINE GABUS

Research assistant

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JUN YU

Post-Doctoral Fellow

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XUEFENG ZHANG

Post-Doctoral Fellow

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MARGHERITA BOTTO

Post-Doctoral Fellow

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ANNA HÖFLER

PhD student

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LINA POULAIN

PhD student

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SOPHIA SCHMIDT

PhD student

 

PUBLICATIONS

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RESEARCH PUBLICATIONS

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REVIEWS

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OTHER DOCUMENTS

Read More
 
 
 

CONTACT US

Boland laboratory
Department of Molecular and Cellular Biology (MOCEL)
Sciences III
30 Quai Ernest-Ansermet
1211 Geneva, Switzerland

+41 22 379 61 27

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FUNDING

Funding