Welcome to the Boland lab!

We are a friendly, focused and enthusiastic group working at the intersection of Structural Biology, Molecular Biology and Cell Biology. We leverage the latest developments in Structural Biology, and here in particular cryo-electron microscopy (cryo-EM) with complementary biophysical techniques (proteomics, light-microscopy, microfluidics, etc.), to adress complex biological questions in the field of cell cycle regulation and cell signaling.

LATEST NEWS

WELCOME TO THE LAB XUEFENG!

We are very happy to have you as part of our lab and look forward to your start in September. Your expertise in GPCR purification will be a great asset to the group. Welcome, and we wish you great success!

PAPER ON S100A9 OUT IN NATURE COMMUNICATIONS

A collaboration with the Coppari group at the University of Geneva on S100A9 is now out in Nature Communications. Anna Höfler purified recombinant proteins used for in vivo studies.

https://www.nature.com/articles/s41467-022-31803-5.pdf

THE APC/C AT SUB-3 Å RESOLUTION

Anna and Jun have deposited the first sub-3 Å structure to the EMDB/PDB of the Anaphase-promoting complex/cyclosome (APC/C) - even before paper publication (see structure gallery). We hope that the more complete and accurate model will already be useful for scientists working on cell cycle regulation.
PDB code: 7QE7, release date: 22.12.22

PROJECT FUNDED!

A new collaboration between the Stoeber lab at the CMU (Faculty of Medicine) and the Boland lab (Faculty of Sciences). Very much looking forward to this project, Miriam & coworkers!